Drawing Conclusions: What Are Different Types of Genetic Disorders?

Different Types of Genetic Disorders -HoloprosencephalyName
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Different Types of Genetic Disorders -HoloprosencephalyHoloprosencephaly is a structural disorder of the brain which occurs when the brain fails to divide into the left and right hemisphere. Early child development periods.it can affect both the brain and the face. It is a genetic disease that includes continuum malformations of the lobar, middle interhemispheric variant type HPE and semi-lobar. Holoprosencephaly (HPE)is caused by some types of chromosomal abnormalities, and mutation. The risk of the family getting HPE depends on specific causes of HPE in the family. It occurs when HPE is passed in an autosomal dominant mode from the parent to the child. If mutation or change occurs in a copy of the responsible gene, then each cell is enough to cause the condition in the individual and the successive generations.
In cases where the parents have autosomal dominant nonsyndromic HPE, the children have got high chances of contracting the disease. Whereas those whose parents received the disease through a mutation that leads to autosomal dominant of HPE have got 50% risk of inheriting the disease from the parent (Singh, Sharma, Agarwal & Kalra, 2018). For instance, individuals with severe malformation such as lobar holoprosencephaly suffers the problem of mental retardation and other illnesses that are difficult to treat. The condition is also associated with the problems of facial malformations of the eye, lips, and nose.

The gene of holoprosencephaly is mostly inherited from the mother, only in few cases does it come from the father. The molecular genetic testing experiment can be used to test if any new drug found is effective in treating the disorder or not. Teratogenic elements can be used as an independent control variable and use of non-teratogenic components to dependent variable test. Imaging of the brain by CT scan can be used to check if the disorder has been treated or if persist.
In conclusion, Holoprosencephaly is a very dangerous disease to the brain which should be eliminated as fast as possible after it has been realized. People who come from the lineage with the disease, or whose parents possess the autosomal dominant HPE or mutative autosomal dominant HPE should seek an immediate diagnosis. If one is dragonized of the disease, then they should find the rectification criteria before siring. The victims of the unfortunate disorder should be granted the required protection and guidance.

References
Singh, K., Sharma, S., Agarwal, K., & Kalra, A. (2018). Cyclopia-otocephaly-agnathia-synotia-astomia complex: A case report. Journal of Clinical Neonatology, 7(3), 177–180. https://doi.org/10.4103/jcn.JCNpass:[_]23_18